Fed up with her parents' bickering, poor-little-rich-girl Maya (Dylan Penn) moves in with her boyfriend who is squatting in an old, condemned building on Manhattan's Lower East Side. With neighbors that are meth heads, junkies and degenerates, this depraved hell hole is even more toxic than it appears: After a virus born from their combined noxious waste and garbage infects the building's residents, one by one, they succumb to a terrifying pathogen that turns them into bloodthirsty, rampaging killers and transforms their building into a savage slaughterhouse.

A bullied teenager is sent to a reform school where he accidentally summons the spirit of a girl, herself a victim of bullying, who takes vengeance on his tormentors.

In a wintry small town, the body of a teenager named Jamie Marks is found by the river. Adam, the star of his cross-country team, becomes fascinated with Jamie-a boy nobody really knew or interacted with, except occasionally to bully him. When Jamie's ghost begins to appear both to Adam and Gracie, the classmate who discovered the body, Adam is caught between two worlds. He has a budding romance with Gracie, but he also feels a deep connection to Jamie, who brings him closer to the world of the undead.

Lila wants to emulate the sexual exploits of her more experienced best friend. She fixates on a tough older guy who will "sleep with anyone" and tries to insert herself into his world, putting herself in a dangerously vulnerable situation.